zidovudineEnglishOxford Dictionary of Englishzidovudine /zɪˈdɒvjʊdiːn , zɪˈdəʊvjʊdiːn / ▸ noun [mass noun] Medicine an antiviral drug used in the treatment of AIDS. It slows the growth of HIV infection in the body, but is not curative. A thymidine derivative; chemical formula: C10H13N5O4. – ORIGIN 1980s; arbitrary alteration of azidothymidine.