ubiquitinEnglishOxford Dictionary of Englishubiquitin /juːˈbɪkwɪtɪn / ▸ noun [mass noun] Biochemistry a compound found in living cells which plays a role in the degradation of defective and superfluous proteins. It is a single-chain polypeptide. – ORIGIN 1970s: from ubiquitous + -in1.