xyleneEnglishOxford New American Dictionaryxylene /ˈzīlēn, ˈzaɪlin / ▸ noun Chemistry a volatile liquid hydrocarbon obtained by distilling wood, coal tar, or petroleum, used in fuels and solvents and in chemical synthesis. Alternative name: dimethylbenzene; chemical formula: C6H4(CH3)2; three isomers. – ORIGIN mid 19th century : from xylo- ‘of wood’ + -ene.