quadrupletEnglishOxford New American Dictionaryquadruplet /kwäˈdro͞oplət, kwɑˈdruplət / ▸ noun 1 (usually quadruplets) each of four children born at one birth. 2 Music a group of four notes to be performed in the time of three. – ORIGIN late 18th century : from quadruple, on the pattern of triplet.