jackedEnglishOxford New American Dictionaryjacked /jakt, dʒækt / (also jacked up) ▸ adjective informal, mainly US 1 physically or mentally stimulated from the effects of a drug or stimulant: a race car driver, jacked up on amphetamines. ▪ full of nervous excitement: we're jacked about going to the semifinals. 2 (of a person) having very well-developed muscles: a dude so jacked you have to wonder if he's freebasing creatine.