killerEnglishOxford English Thesauruskiller noun 1 police are searching for clues to help find the killer: murderer, slaughterer, destroyer, liquidator, exterminator, terminator, executioner; literary slayer; dated homicide. 2 the major killers are coronary disease, stroke, and cancer: cause of death, fatal/deadly illness, destroyer, threat to life, menace, plague, scourge, peril.killer Oxford Dictionary of English