safeguardEnglishOxford American Thesaurussafeguard noun early warning provides a safeguard against operational crises: protection, defense, guard, shelter, screen, buffer, preventive, precaution, prophylactic, provision, security, safety measure, surety, cover, insurance, indemnity.verb the contract will safeguard about 1000 jobs: protect, afford protection to, shield, screen, defend, guard, keep safe, shelter; preserve, conserve, look after, save, secure. ▷antonyms jeopardize.