damaging
adjective
pesticides have had a damaging effect on a lot of wildlife:
harmful, detrimental, injurious, hurtful, inimical, dangerous, destructive, ruinous, calamitous, disastrous, deleterious, pernicious, ill, bad, evil, baleful, malign, corrupting, malignant, adverse, undesirable, prejudicial, unfavorable, unfortunate, counterproductive;
unhealthy, unwholesome, poisonous, cancerous, noxious, environmentally unfriendly;
literary malefic, maleficent;
rare prejudicious.
▷antonyms benign; beneficial.