catastrophe
noun
the bush fires were the latest in a growing list of catastrophes:
disaster, calamity, cataclysm, crisis, holocaust, ruin, ruination, tragedy, blow, shock;
adversity, blight, trouble, trial, tribulation, mishap, misfortune, mischance, misadventure, accident, failure, reverse, woe, affliction, distress;
informal meltdown, whammy;
British, informal car crash;
archaic bale;
Scottish, archaic mishanter.
▷antonyms salvation, godsend.